Fig. 8: Transient binding of T4-Lymphocytes to Dendritic Cells

As naive T4-lymphocytes migrate through the cortical region of lymph nodes, they use surface cell adhesion molecules such as LFA-1 and CD2 to bind transiently to corresponding receptors such as ICAM-1, ICAM-2 and CD58 on the surface of dentritic cells. This transient binding allows time for the TCRs on the T8-lymphocyte to sample large numbers of MHC-II/peptide complexes on the antigen-presenting dendritic cells.

 
Illustration of Transient binding of T4-Lymphocytes to Dendritic Cells .jpg by Gary E. Kaiser, Ph.D.
Professor of Microbiology, The Community College of Baltimore County, Catonsville Campus
This work is licensed under a Creative Commons Attribution 4.0 International License.
Based on a work at https://cwoer.ccbcmd.edu/science/microbiology/index_gos.html.

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Last updated: August, 2019
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